After being initiated into a coven of island witches, Neva begins to fulfill her fate in a Tenderloin dive bar. Her worshippers include Richard, the introverted, alcoholic, occasionally omniscient narrator; a profane, aggressive transgender sex worker named Shantelle; the brisk but motherly barmaid Francine; and the former Frank, who has renamed herself after her idol Judy Garland. When Judy starts to love Neva too much, Judy's retired policeman boyfriend embarks on a mission of exposure and destruction.

Crafted out of language by turns spiritual and sexually graphic, The Lucky Star aches with compassion as it explores celebrity culture, gender identity, incest, Christian sacrifice and, most of all, the quotidian and sometimes faltering heroism of marginalized people who in the face of humiliation and outright violence seek to love in their own way, and stand up for who they are.